Wilson W H, Ban T A, Guy W
Neuropsychobiology. 1985;14(2):75-82. doi: 10.1159/000118208.
Prescription practices were examined as part of a multinational study of chronic hospitalized schizophrenic patients. The study included a total of 768 patients from 8 countries. All patients had a diagnosis (ICD-9) of schizophrenia and met defined criteria for chronic hospitalization. The patients were treated with psychotropic drugs from 6 categories, i.e., neuroleptics, antidepressants, lithium salts, anxiolytics, anticonvulsants, and antiparkinsonian medications, as well as with a variety of nonpsychotropic drugs. The majority of the patients received concurrently more than 1 neuroleptic, medications from 2 or more categories, and neuroleptics combined with other agents. Polypharmacy appeared to be universal in this population.
作为一项针对慢性住院精神分裂症患者的跨国研究的一部分，对处方用药情况进行了调查。该研究共纳入了来自8个国家的768名患者。所有患者均根据国际疾病分类第九版（ICD - 9）被诊断为精神分裂症，且符合慢性住院的既定标准。这些患者接受了6类精神药物治疗，即抗精神病药、抗抑郁药、锂盐、抗焦虑药、抗惊厥药和抗帕金森病药物，以及多种非精神药物。大多数患者同时服用超过1种抗精神病药、来自2类或更多类别的药物，以及抗精神病药与其他药物联用。在这一人群中，联合用药似乎很普遍。
