Edwards S, Kumar V
Br J Psychiatry. 1984 Nov;145:502-7. doi: 10.1192/bjp.145.5.502.
Of 603 patients receiving in-patient or day-patient psychiatric care, one-sixth were taking no psychotropic drugs, but nearly 50% of those receiving medication had a combination of two or more such drugs. Hypnotics and minor tranquillisers were frequently prescribed together with neuroleptics and antidepressants. One-third of all patients receiving neuroleptics received a combination of oral and depot preparations, while half of all patients on neuroleptics were prescribed anti-parkinsonian drugs. One-fifth of patients treated with neuroleptics had a diagnosis other than schizophrenia, and one-third of patients treated with antidepressants had a diagnosis other than affective disorder. A comparison of our findings with those from Oxford show some significant differences, particularly in the use of depot, oral, of combined neuroleptic drugs. An analysis of prescribing could be a useful part of self-audit for hospitals.
在603名接受住院或日间精神病护理的患者中,六分之一未服用任何精神药物,但在接受药物治疗的患者中,近50%同时服用两种或更多种此类药物。催眠药和小剂量镇静剂经常与抗精神病药和抗抑郁药一起开。所有接受抗精神病药治疗的患者中有三分之一同时接受口服制剂和长效制剂,而所有服用抗精神病药的患者中有一半同时服用抗帕金森病药物。接受抗精神病药治疗的患者中有五分之一的诊断不是精神分裂症,接受抗抑郁药治疗的患者中有三分之一的诊断不是情感障碍。将我们的研究结果与牛津的研究结果进行比较,发现了一些显著差异,特别是在长效、口服和联合抗精神病药物的使用方面。处方分析可能是医院自我审核的一个有用部分。