Worth V, Perry R, Ireland T, Wills A K, Sandy J, Ness A
University of Bristol, Bristol Nutrition BRU, University Hospitals Bristol Education and Research Centre, Upper Maudlin Street, Bristol, Bristol, BS2 8AE.
Child Dental Health, Bristol Dental Hospital, Lower Maudlin Street, Bristol, BS1 2LY.
Br Dent J. 2017 Jul 7;223(1):37-47. doi: 10.1038/sj.bdj.2017.581.
Objective To establish whether children born with an orofacial cleft have a higher risk of dental caries than individuals without cleft.Design A systematic review and meta-analysisMethods The search strategy was based on the key words 'cleft lip palate' and 'oral hygiene caries decay'. Ten databases were searched from their inception to April 2016 to identify all relevant studies. All data were extracted by two independent reviewers. The primary outcome measure was caries measured by the decayed, missing, filled surfaces/teeth index (dmfs/dmft or DMFS/DMFT).Results Twenty-four studies met the selection criteria. All of the studies were observational. Twenty-two studies were suitable for inclusion in the meta-analysis. The overall pooled mean difference in dmft was 0.63 (95% CI: 0.47 to 0.79) and in DMFT was 0.28 (95% CI: 0.22 to 0.34).Conclusion Individuals with cleft lip and/or palate have higher caries prevalence, both in the deciduous and the permanent dentitions.
目的 确定患有口腔颌面裂的儿童患龋齿的风险是否高于无口腔颌面裂的个体。
设计 系统评价和荟萃分析
方法 检索策略基于关键词“唇腭裂”和“口腔卫生 龋齿 蛀牙”。检索了10个数据库自建库至2016年4月期间的所有相关研究。所有数据由两名独立的评审员提取。主要结局指标为通过龋失补牙面/牙指数（dmfs/dmft或DMFS/DMFT）测量的龋齿。
结果 24项研究符合纳入标准。所有研究均为观察性研究。22项研究适合纳入荟萃分析。dmft的总体合并平均差为0.63（95%CI：0.47至0.79），DMFT的总体合并平均差为0.28（95%CI：0.22至0.34）。
结论 唇裂和/或腭裂个体在乳牙列和恒牙列中的龋齿患病率均较高。
