Szweda Roza, Chendo Christophe, Charles Laurence, Baxter Paul N W, Lutz Jean-François
Université de Strasbourg, CNRS, Institut Charles Sadron UPR22, 23 rue du Loess, 67034 Strasbourg Cedex 2, France.
Chem Commun (Camb). 2017 Jul 20;53(59):8312-8315. doi: 10.1039/c7cc03633g.
Due to their strong tendency to self-aggregate, unfunctionalized oligoarylacetylenes are difficult to synthesize. Here, tailored polystyrene soluble supports, prepared by atom transfer radical polymerization and post-polymerization modification, were tested for preparing sequence-defined oligoarylacetylenes. Controlled aromatic sequences were obtained by iterative Sonogarisha coupling, using phenyl- and pyridine-based building-blocks.
由于未官能化的低聚芳基乙炔具有很强的自聚集倾向，因此难以合成。在此，通过原子转移自由基聚合和聚合后修饰制备的定制聚苯乙烯可溶性载体，被用于制备序列定义的低聚芳基乙炔。使用基于苯基和吡啶的构建块，通过迭代的Sonogarisha偶联获得了可控的芳族序列。
