低级别和高级别透明细胞肾细胞癌的鉴别：肿瘤大小与CT灌注参数
Differentiation of low- and high-grade clear cell renal cell carcinoma: Tumor size versus CT perfusion parameters.
作者信息
Chen Chao, Kang Qinqin, Xu Bing, Guo Hairuo, Wei Qiang, Wang Tiegong, Ye Hui, Wu Xinhuai
机构信息
Department of Radiology, PLA Army General Hospital, Beijing 100700, China.
Department of Radiology, Changhai Hospital of Shanghai, The second Military Medical University, Shanghai 200433, China.
出版信息
Clin Imaging. 2017 Nov-Dec;46:14-19. doi: 10.1016/j.clinimag.2017.06.010. Epub 2017 Jul 3.
PURPOSE
To compare the utility of tumor size and CT perfusion parameters for differentiation of low- and high-grade clear cell renal cell carcinoma (RCC).
MATERIALS AND METHODS
Tumor size, Equivalent blood volume (Equiv BV), permeability surface-area product (PS), blood flow (BF), and Fuhrman pathological grading of clear cell RCC were retrospectively analyzed.
RESULTS
High-grade clear cell RCC had significantly higher tumor size and lower PS than low grade. Tumor size positively correlated with Fuhrman grade, but PS negatively did.
CONCLUSIONS
Tumor size and PS were significantly independent indexes for differentiating high-grade from low-grade clear cell RCC.
目的
比较肿瘤大小和CT灌注参数在鉴别低级别和高级别透明细胞肾细胞癌（RCC）中的作用。
材料与方法
回顾性分析透明细胞RCC的肿瘤大小、等效血容量（Equiv BV）、通透表面积乘积（PS）、血流量（BF）和福尔曼病理分级。
结果
高级别透明细胞RCC的肿瘤大小显著高于低级别，而PS显著低于低级别。肿瘤大小与福尔曼分级呈正相关，而PS呈负相关。
结论
肿瘤大小和PS是鉴别高级别与低级别透明细胞RCC的显著独立指标。
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