Li Yu, Dai Chunfu
Department of the Otology and Skull Base Surgery, Eye and Eye Ear Nose and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Hearing Medicine Key Laboratory of Ministry of Health, Eye Ear Nose and Throat Hospital, Fudan University, Shanghai, China.
Eur Arch Otorhinolaryngol. 2017 Sep;274(9):3359-3366. doi: 10.1007/s00405-017-4665-x. Epub 2017 Jul 7.
The objective is to increase awareness of facial nerve schwannomas (FNSs). Clinical data from 32 cases with FNSs who received surgical treatment from 2005 to 2015 were reviewed retrospectively. The clinical data included age, sex, presentations, duration, facial nerve function, temporal-bone high-resolution computed tomography (CT) and magnetic resonance imaging (MRI) findings, surgical approaches, and postoperative histopathological examination. 16 men and 16 women were included, aged 7-69 years. The average age at diagnosis was approximately 44 years. The mean duration of disease was 65 months, and the mean tumor diameter was 22.4 mm. A tendency of multisegment involvement was observed in 29 FNS cases. Geniculate ganglion and tympanic segments were the most commonly involved segments. Meanwhile, the incidence of misdiagnosis of this disease was 50%. We observed that when FNSs involved the proximal portion of genicular ganglion, the hearing function tended to be worse than when the FNSs only involved the genicular ganglion and/or its distal portion (p < 0.05); in such cases, the hearing loss tended to become more severe with a longer duration of the disorder (p < 0.05). Multiple segment involvement is common in patients with FNS. We need to be more aware of the hearing function when FNSs involve the proximal portion of genicular ganglion. Misdiagnoses of FNS are common, and patients can be misdiagnosed with Bell's palsy, otitis media, or other diseases. Image studies should be conducted for differential diagnosis. Once the decision to perform surgical resection was made, reconstruction of the facial nerve should be considered.
目的是提高对面神经鞘瘤(FNSs)的认识。回顾性分析了2005年至2015年接受手术治疗的32例FNSs患者的临床资料。临床资料包括年龄、性别、临床表现、病程、面神经功能、颞骨高分辨率计算机断层扫描(CT)和磁共振成像(MRI)结果、手术方式及术后组织病理学检查。纳入16例男性和16例女性,年龄7 - 69岁。诊断时的平均年龄约为44岁。疾病的平均病程为65个月,肿瘤平均直径为22.4毫米。在29例FNS病例中观察到多节段受累的倾向。膝状神经节和鼓室段是最常受累的节段。同时,该疾病的误诊率为50%。我们观察到,当FNSs累及膝状神经节近端时,听力功能往往比仅累及膝状神经节和/或其远端时更差(p < 0.05);在这种情况下,随着疾病持续时间延长,听力损失往往会变得更严重(p < 0.05)。多节段受累在FNS患者中很常见。当FNSs累及膝状神经节近端时,我们需要更加关注听力功能。FNS的误诊很常见,患者可能被误诊为贝尔面瘫、中耳炎或其他疾病。应进行影像学检查以进行鉴别诊断。一旦决定进行手术切除,就应考虑面神经重建。