Mirza Shireen, Benzo Roberto
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
Mayo Clin Proc. 2017 Jul;92(7):1104-1112. doi: 10.1016/j.mayocp.2017.03.020.
Chronic obstructive pulmonary disease (COPD) phenotyping can help define clusters of patients with common characteristics that relate to clinically meaningful outcomes. In this review, we describe 7 clinically meaningful COPD phenotypes that can be identified by primary care physicians as well as specialists and that have specific management and prognostic implications: (1) asthma-COPD overlap phenotype, (2) frequent exacerbator phenotype, (3) upper lobe-predominant emphysema phenotype, (4) rapid decliner phenotype, (5) comorbid COPD phenotype, (6) physical frailty phenotype, and (7) emotional frailty phenotype.
慢性阻塞性肺疾病(COPD)表型分析有助于确定具有与临床有意义的结局相关的共同特征的患者群体。在本综述中,我们描述了7种具有临床意义的COPD表型,基层医疗医生以及专科医生均可识别这些表型,且它们具有特定的管理和预后意义:(1)哮喘-COPD重叠表型,(2)频繁急性加重表型,(3)上叶为主型肺气肿表型,(4)快速进展表型,(5)合并症COPD表型,(6)身体虚弱表型,以及(7)情绪虚弱表型。