Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass.
Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass.
Am J Med. 2022 Apr;135(4):430-434. doi: 10.1016/j.amjmed.2021.09.027. Epub 2021 Oct 31.
Extracranial carotid atherosclerotic disease has been associated with approximately 15%-20% of ischemic stroke cases and is a leading cause of mortality and disability worldwide. Medical, surgical, and endovascular therapies for the prevention of stroke from carotid disease have advanced considerably over the past quarter century. The objective of this review is to outline the clinical presentation of symptomatic carotid artery stenosis and the risk factors associated with development of carotid artery stenosis and then summarize the current evidence-based medical treatment modalities, along with available surgical and endovascular therapies.
颅外颈动脉粥样硬化性疾病与大约 15%-20%的缺血性脑卒中病例有关，是全球范围内导致死亡和残疾的主要原因。过去四分之一个世纪，用于预防颈动脉疾病引起的脑卒中的医学、外科和血管内治疗方法已经取得了相当大的进展。本综述的目的是概述有症状颈动脉狭窄的临床表现，以及与颈动脉狭窄发展相关的危险因素，然后总结当前基于循证的医学治疗方法，以及现有的外科和血管内治疗方法。
