Prakash Nachiketh Soodana, Lopategui Diana M, Gomez Christopher
Department of Urology, Miller School of Medicine University of Miami, Miami, FL, USA.
Curr Urol Rep. 2017 Aug;18(8):64. doi: 10.1007/s11934-017-0707-6.
Bladder compliance is a measure of distensibility. Maladies such as myelodysplasia, myelomeningocele, spinal cord injury, multiple sclerosis and obstructive uropathy are known to decrease bladder compliance. Decrease in bladder compliance is a characteristic of neurogenic bladders. The pathophysiology of bladder compliance is complex but ultimately leads to high pressure during filling and storage phases. These high pressures lead to renal impairment, incontinence, and recurrent urinary tract infections. This review presents management of poorly compliant bladders with onabotulinumtoxinA.
膀胱顺应性是对扩张性的一种衡量。诸如脊髓发育不良、脊髓脊膜膨出、脊髓损伤、多发性硬化症和梗阻性尿路病等疾病已知会降低膀胱顺应性。膀胱顺应性降低是神经源性膀胱的一个特征。膀胱顺应性的病理生理学很复杂，但最终会导致充盈期和储尿期的高压。这些高压会导致肾功能损害、尿失禁和反复的尿路感染。本综述介绍了用A型肉毒毒素治疗顺应性差的膀胱的方法。
