Zhou Ying, Song Runxu, Diwu Danbei, Wan Yixin
Department of Respiratory Disease, Second Hospital of Lanzhou University, Lanzhou 730030, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2017 Jun 28;42(6):720-724. doi: 10.11817/j.issn.1672-7347.2017.06.019.
Idiopathic pulmonary fibrosis (IPF) is one of the most common idiopathic interstitial pneumonia. The main symptoms for IPF are dry cough and exertional shortness of breath, which is worsen gradually with the development of pulmonary fibrosis. Patients with IPF often suffer from sleep disordered breathing (SDB). Sleep architecture for these patients including the sleep efficiency, deep sleep, rapid eye movement sleep and arousal index, are changed, which seriously affects the quality of life. In the absence of effective therapies, optimizing the quality of life may become a major therapeutic target for IPF. The diagnosis and treatment of SDB can significantly improve the quality of life for patients with IPF.
特发性肺纤维化（IPF）是最常见的特发性间质性肺炎之一。IPF的主要症状是干咳和劳力性气短，随着肺纤维化的发展会逐渐加重。IPF患者常伴有睡眠呼吸障碍（SDB）。这些患者的睡眠结构，包括睡眠效率、深度睡眠、快速眼动睡眠和觉醒指数都发生了改变，严重影响生活质量。在缺乏有效治疗方法的情况下，优化生活质量可能成为IPF的主要治疗目标。SDB的诊断和治疗可显著提高IPF患者的生活质量。
