人乳头瘤病毒16型E7抗原的线性表位预测及其与人TMEM 50A结构模型的对接相互作用

Linear epitope prediction in HPV type 16 E7 antigen and their docked interaction with human TMEM 50A structural model.

作者信息

Srivastava Upasna, Singh Satendra, Gautam Budhyash, Yadav Pramod, Yadav Madhu, Thomas George, Singh Gurmit

机构信息

Department of Computational Biology and Bioinformatics, Sam Higginbottom Institute of Agriculture, Technology and Sciences,Allahabad-211007, India.

Jacob School of Biotechnology and Bioengineering, Sam Higginbottom Institute of Agriculture, Technology and Sciences, Allahabad-211007, India.

出版信息

Bioinformation. 2017 May 31;13(5):122-130. doi: 10.6026/97320630013122. eCollection 2017.

Human Papilloma Virus (HPV) HPV type 16 E7 antigen is a known target in cervical cancer. We report the predicted potential epitopes in the E7 antigen. We further describe the subsequent interaction of these linear epitope peptides with the human TMEM 50 A structural model using molecular docking. This data finds application in the development of components towards HPV associated disease prevention.