Schneidman-Duhovny Dina, Inbar Yuval, Nussinov Ruth, Wolfson Haim J
School of Computer Science, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W363-7. doi: 10.1093/nar/gki481.
Here, we describe two freely available web servers for molecular docking. The PatchDock method performs structure prediction of protein-protein and protein-small molecule complexes. The SymmDock method predicts the structure of a homomultimer with cyclic symmetry given the structure of the monomeric unit. The inputs to the servers are either protein PDB codes or uploaded protein structures. The services are available at http://bioinfo3d.cs.tau.ac.il. The methods behind the servers are very efficient, allowing large-scale docking experiments.
在此，我们介绍两个免费的分子对接网络服务器。PatchDock方法可对蛋白质-蛋白质和蛋白质-小分子复合物进行结构预测。SymmDock方法在给定单体单元结构的情况下，预测具有环状对称性的同多聚体的结构。服务器的输入可以是蛋白质PDB代码或上传的蛋白质结构。这些服务可在http://bioinfo3d.cs.tau.ac.il获取。服务器背后的方法非常高效，能够进行大规模对接实验。
