The Age of the Father.
作者信息
Poot Martin
出版信息
Mol Syndromol. 2017 Jun;8(4):169-171. doi: 10.1159/000471776. Epub 2017 Apr 20.
Abstract
摘要
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本文引用的文献
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Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation.父亲年龄对精子中FOXK1和KCNA7甲基化的影响及其向下一代的传递。
Hum Mol Genet. 2016 Nov 15;25(22):4996-5005. doi: 10.1093/hmg/ddw328.
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Paternal age and psychiatric disorders: A review.父亲年龄与精神障碍：综述
Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):202-213. doi: 10.1002/ajmg.b.32508. Epub 2016 Oct 22.
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Examining genotypic variation in autism spectrum disorder and its relationship to parental age and phenotype.研究自闭症谱系障碍的基因变异及其与父母年龄和表型的关系。
Appl Clin Genet. 2016 Jul 28;9:121-9. doi: 10.2147/TACG.S112712. eCollection 2016.
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Genome-wide characteristics of mutations in autism.自闭症中突变的全基因组特征
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CpG sites with continuously increasing or decreasing methylation from early to late human fetal brain development.在人类胎儿大脑从早期到晚期发育过程中甲基化持续增加或减少的CpG位点。
Gene. 2016 Oct 30;592(1):110-118. doi: 10.1016/j.gene.2016.07.058. Epub 2016 Jul 25.
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Mechanisms of Origin, Phenotypic Effects and Diagnostic Implications of Complex Chromosome Rearrangements.复杂染色体重排的起源机制、表型效应及诊断意义
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Chromothripsis: potential origin in gametogenesis and preimplantation cell divisions. A review.染色体碎裂：配子发生和植入前细胞分裂中的潜在起源。综述
Fertil Steril. 2014 Dec;102(6):1785-96. doi: 10.1016/j.fertnstert.2014.09.006. Epub 2014 Oct 18.
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The phenotypic manifestations of rare genic CNVs in autism spectrum disorder.自闭症谱系障碍中罕见基因拷贝数变异的表型表现。
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Nature. 2014 Nov 13;515(7526):216-21. doi: 10.1038/nature13908. Epub 2014 Oct 29.
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Age-related sperm DNA methylation changes are transmitted to offspring and associated with abnormal behavior and dysregulated gene expression.与年龄相关的精子 DNA 甲基化变化会传递给后代，并与异常行为和基因表达失调有关。
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