Uhliarová B, Bugová G, Jeseňák M, Pechacova S, Hamarova M, Hajtman A
Epidemiol Mikrobiol Imunol. 2017 Summer;66(2):67-72.
To evaluate microbial colonization of upper aerodigestive tract in children and to investigate the influence of adenoid hypertrophy, allergy and exposition to cigarette smoke on presence of pathogens.
In 43 children with adenoid hypertrophy and 17 healthy children bacterial culture was performed by a swab from middle nasal meatus, nasopharynx and tonsils. The effect of adenotomy, presence of allergy and exposure to passive smoking on bacterial colonization were investigated.
Identification of potentially pathogenic bacteria in upper aerodigestive tract was significantly higher in children with adenoid hypertrophy compare to control group. Adenotomy was associated with significantly decreased colonization by potential pathogens. Allergy was diagnosed in 33 % children with adenoid hypertrophy. Presence of allergy and exposure to tobacco smoke were associated with significantly more often colonization by potentially pathogenic bacteria in the upper aerodigestive tract.
Increased colonization of upper aerodigestive tract by potential pathogens and their significant decrease after adenotomy indicate the role of pathogenic bacteria in the etiopathogenesis of adenoid hypertrophy. Allergy and tobacco smoke exposure are related to increased colonization by potentially pathogenic bacteria in the upper aerodigestive tract.
评估儿童上气道消化道的微生物定植情况，并研究腺样体肥大、过敏和接触香烟烟雾对病原体存在的影响。
对43例腺样体肥大儿童和17例健康儿童，通过取自中鼻道、鼻咽和扁桃体的拭子进行细菌培养。研究腺样体切除术、过敏情况和被动吸烟暴露对细菌定植的影响。
与对照组相比，腺样体肥大儿童上气道消化道中潜在病原菌的检出率显著更高。腺样体切除术与潜在病原菌定植显著减少相关。33%的腺样体肥大儿童被诊断为过敏。过敏和接触烟草烟雾与上气道消化道中潜在病原菌定植明显更频繁相关。
潜在病原菌在上气道消化道中的定植增加以及腺样体切除术后其显著减少，表明病原菌在腺样体肥大的病因发病机制中起作用。过敏和烟草烟雾暴露与上气道消化道中潜在病原菌定植增加有关。
