Lipszyc Joshua C, Silverman Frances, Holness Dorothy Linn, Liss Gary M, Lavoie Kim L, Tarlo Susan M
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada (Mr Lipszyc, Drs Silverman, Holness, Tarlo); Toronto Western Hospital, Toronto, Ontario, Canada (Mr Lipszyc, Dr Tarlo); University Health Network, Toronto, Ontario, Canada, Respiratory Division (Dr Tarlo); Department of Occupational and Environmental Health, St. Michael's Hospital, Toronto, Ontario, Canada (Mr Lipszyc, Drs Silverman, Holness, Tarlo); Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (Drs Silverman, Tarlo); Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (Dr Holness); Department of Medicine, University of Toronto, Toronto, Ontario, Canada (Drs Silverman, Holness, Tarlo); Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada (Drs Silverman, Holness, Liss, Tarlo); Montreal Behavioural Medicine Centre, Research Centre, Centre Intégré universitaire de santé et de services sociaux du Nord de l'Ile (CIUSSS-NIM) - Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada (Dr Lavoie); Université du Québec à Montréal (UQAM), Montréal, Quebec, Canada (Dr Lavoie).
J Occup Environ Med. 2017 Jul;59(7):697-702. doi: 10.1097/JOM.0000000000001066.
The aim of this study was to compare psychological status, quality of life (QoL), work limitation, and socioeconomic status between patients with occupational asthma (OA) and work-exacerbated asthma (WEA).
The following questionnaires were administered to participants: Beck anxiety and depression (II) inventories, Marks' Asthma Quality of Life Questionnaire, and Work Limitations Questionnaire. Cross-sectional analyses between OA and WEA subgroups were completed.
There were 77 participants. WEA subjects had a trend to higher anxiety scores (OA = 9.2 ± 8.0, WEA = 12.8 ± 8.3, P = 0.07, Cohen d = 0.4). Depression scores trended higher for those with WEA (OA = 9.6 ± 10.3, WEA = 13.4 ± 13.5, P = 0.2, Cohen d = 0.3). QoL was comparable between groups. WEA subjects had fewer work limitations (N = 50, OA = 25.1 ± 27.3, WEA = 20.6 ± 24.4, P = 0.56, Cohen d = 0.3) and OA subjects were more likely to have reduced income.
In a tertiary clinic, there were some modest differences for specific variables between OA and WEA subjects that may help inform management.
本研究旨在比较职业性哮喘（OA）患者和工作加重性哮喘（WEA）患者的心理状态、生活质量（QoL）、工作限制及社会经济状况。
向参与者发放以下问卷：贝克焦虑和抑郁（第二版）量表、马克斯哮喘生活质量问卷及工作限制问卷。完成OA和WEA亚组之间的横断面分析。
共有77名参与者。WEA受试者的焦虑得分有升高趋势（OA = 9.2±8.0，WEA = 12.8±8.3，P = 0.07，科恩d值 = 0.4）。WEA患者的抑郁得分也有升高趋势（OA = 9.6±10.3，WEA = 13.4±13.5，P = 0.2，科恩d值 = 0.3）。两组间生活质量相当。WEA受试者的工作限制较少（N = 50，OA = 25.1±27.3，WEA = 20.6±24.4，P = 0.56，科恩d值 = 0.3），且OA受试者更可能收入减少。
在一家三级诊所中，OA和WEA受试者在特定变量上存在一些适度差异，这可能有助于指导管理。
