大气细颗粒物污染与老年 2 型糖尿病患者呼吸系统健康的关系。
The Association Between Particulate Matter Air Pollution and Respiratory Health in Elderly With Type 2 Diabetes Mellitus.
机构信息
Department of Occupational and Environmental Health, School of Public Health, Fudan University (Dr Hao, Mr Wang, Dr Feng, Dr Sun, Dr Chen, Dr Xia); Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (Drs Zhao, Gao), Shanghai; State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Chaoyang District, Beijing (Drs Han, Bai), China; Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, Florida (Dr Zhu).
出版信息
J Occup Environ Med. 2017 Sep;59(9):830-834. doi: 10.1097/JOM.0000000000001077.
OBJECTIVE
We investigated the association between respiratory health and particulate matter (PM) air pollution in elderly type 2 diabetes mellitus (T2DM) pre-, during, and post-the Chinese Lunar New Year (CLNY) holiday in Shanghai, China.
METHODS
We conducted repeated measurements of lung function and inflammation biomarker in a cohort consisted of 60 participants with T2DM.
RESULTS
Decreased PM2.5 exposure had an effect on respiratory health by increasing in forced expiratory flow in 1 second (FEV1) and forced vital capacity (FVC). Positive associations between PM exposure and exhaled nitric oxide (eNO) were observed.
CONCLUSIONS
Our observations indicated that PM air pollution exposure would exert adverse effect on respiratory health in elderly T2DM population.
目的
本研究旨在探讨中国上海地区老年 2 型糖尿病（T2DM）患者在农历新年假期前后，颗粒物（PM）空气污染与呼吸健康之间的关系。
方法
我们对 60 例 T2DM 患者进行了重复的肺功能和炎症生物标志物测量。
结果
PM2.5 暴露减少对呼吸健康有积极影响，表现为一秒用力呼气容积（FEV1）和用力肺活量（FVC）增加。PM 暴露与呼出气一氧化氮（eNO）之间存在正相关关系。
结论
我们的观察结果表明，PM 空气污染暴露可能对老年 T2DM 人群的呼吸健康产生不利影响。
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