Walt R, Katschinski B, Logan R, Ashley J, Langman M
Lancet. 1986 Mar 1;1(8479):489-92. doi: 10.1016/s0140-6736(86)92940-5.
Peptic ulcer admission rates were known to be declining in England and Wales in younger men and women at least until 1977, but rates in elderly men were stable and rates in older women were increasing. Analysis of the most recently available data shows that these trends have continued in England and Wales and similar trends are seen in the elderly populations in Scotland. Reasons for the increasing susceptibility of elderly people, particularly older women, to peptic ulceration are not clear. However, altered smoking habits seem unlikely to explain the change, whereas increased use of non-steroidal anti-inflammatory drugs may account for part of it.
至少在1977年之前，已知英格兰和威尔士年轻男性和女性的消化性溃疡入院率在下降，但老年男性的入院率稳定，老年女性的入院率在上升。对最新可得数据的分析表明，这些趋势在英格兰和威尔士仍在持续，苏格兰老年人群中也出现了类似趋势。老年人，尤其是老年女性，对消化性溃疡易感性增加的原因尚不清楚。然而，吸烟习惯的改变似乎无法解释这一变化，而非甾体抗炎药使用的增加可能是部分原因。
