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[成人Ⅰ型Chiari畸形手术治疗中后颅窝减压术加或不加硬脑膜成形术的比较]

[Comparison of posterior fossa decompression with and without duraplasty for surgical management for adult Chiari malformation type Ⅰ].

作者信息

Li H Y, Li Y M, Chen H, Li Y, Shi X W

机构信息

Department of Neurosurgery, Henan Provincial People's Hospital, Zhengzhou 450003, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2017 Jul 4;97(25):1947-1950. doi: 10.3760/cma.j.issn.0376-2491.2017.25.006.

Abstract

To evaluate and compare the efficacy between posterior fossa decompression without duraplasty (PFD) and posterior fossa decompression with duraplasty (PFDD) in the surgical management for adult Chiari Ⅰ malformation. Fifty-seven patients suffered from Chiari malformation type Ⅰ were treated in Department of Neurosurgery, Henan Provincial People's Hospital from August 2008 to October 2013. Twenty-three patients received posterior fossa decompression without duraplasty and the other 34 patients received posterior fossa decompression with duraplasty. The clinical results were retrospectively analyzed to compare the efficacy of two different surgical approaches. There was no death or severe neurological dysfunction case in 57 patients of the two groups. Patients undergoing PFD had shorter length of hospital stay[(13.7±3.5) d vs (16.2±4.1) d, <0.05]and surgical time[(98.7±22.1) min vs (132.3±39.6)min, <0.05]. Cerebrospinal fluid-related complications and intracranial infection were more common in patients undergoing PFDD[(0/23, 0) vs (8/34, 23.5%), <0.05]. Clinical improvement was comparable in two groups[(15/23, 65.2%) vs (26/34, 76.5%), >0.05]at the one-year follow-up. The rate of syrinx regression in patients with Syringomyelia was higher in patients undergoing PFDD[(3/12, 25%) vs (17/22, 77.3%), <0.05]. For adult patients with Chiari malformation type Ⅰ, PFD has the advantages of simple manipulation, short length of hospital stay and low incidence of cerebrospinal fluid-related complications and intracranial infection, compared with PFDD. It is comparable to PFDD in clinical improvement, but the effect of PFD is not as good as that of PFDD in the aspect of syrinx regression.

摘要

评估并比较单纯后颅窝减压术(PFD)与后颅窝减压联合硬脑膜成形术(PFDD)在成人 Chiari Ⅰ型畸形手术治疗中的疗效。2008年8月至2013年10月,河南省人民医院神经外科收治了57例 Chiari Ⅰ型畸形患者。其中23例行单纯后颅窝减压术,34例行后颅窝减压联合硬脑膜成形术。对临床结果进行回顾性分析,以比较两种不同手术方式的疗效。两组57例患者均无死亡或严重神经功能障碍病例。接受PFD的患者住院时间较短[(13.7±3.5)天 vs (16.2±4.1)天,<0.05],手术时间较短[(98.7±22.1)分钟 vs (132.3±39.6)分钟,<0.05]。PFDD患者脑脊液相关并发症和颅内感染更为常见[(0/23,0) vs (8/34,23.5%),<0.05]。在一年随访时,两组临床改善情况相当[(15/23,65.2%) vs (26/34,76.5%),>0.05]。脊髓空洞症患者中,PFDD患者脊髓空洞缩小率更高[(3/12,25%) vs (17/22,77.3%),<0.05]。对于成人 Chiari Ⅰ型畸形患者,与PFDD相比,PFD具有操作简单、住院时间短、脑脊液相关并发症和颅内感染发生率低的优点。其临床改善情况与PFDD相当,但在脊髓空洞缩小方面,PFD的效果不如PFDD。

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