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意外将类固醇注射入晶状体。

Inadvertent steroid injection into the crystalline lens.

作者信息

Alam Md Shahid, Khetan Vikas

机构信息

Orbit, Oculoplasty, Reconstructive & Aesthetic Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

Bhagwan Mahavir Vitreoretina Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

出版信息

GMS Ophthalmol Cases. 2017 Jun 27;7:Doc16. doi: 10.3205/oc000067. eCollection 2017.

DOI:10.3205/oc000067
PMID:28695074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5488069/
Abstract

Intravitreal triamcinolone is administered for a wide number of vitreoretinal conditions. Several complications including cataract formation, raised intraocular pressure, and endophthalmitis have been reported following intravitreal injections. We report a rare case wherein triamcinolone was inadvertently injected directly into the crystalline lens. A 41-year-old male presented to us with a history of intravitreal injection of triamcinolone in the left eye 2 weeks earlier. Slit lamp examination revealed a needle tract in the crystalline lens with steroid granules dispersed throughout the lens core. Such a complication is extremely rare with only three cases reported previously.

摘要

玻璃体内注射曲安奈德可用于多种玻璃体视网膜疾病。玻璃体内注射后,已有数种并发症被报道,包括白内障形成、眼压升高和眼内炎。我们报告一例罕见病例,曲安奈德被意外直接注射入晶状体。一名41岁男性2周前左眼接受了玻璃体内曲安奈德注射,随后前来就诊。裂隙灯检查发现晶状体有针道,类固醇颗粒散布于整个晶状体核。这种并发症极为罕见,此前仅报道过3例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee68/5488069/83ea95bd3987/OC-07-16-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee68/5488069/83ea95bd3987/OC-07-16-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee68/5488069/83ea95bd3987/OC-07-16-g-001.jpg

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Int J Ophthalmol. 2020 Dec 18;13(12):1864-1871. doi: 10.18240/ijo.2020.12.04. eCollection 2020.

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Update on corticosteroids for diabetic macular edema.糖尿病性黄斑水肿的皮质类固醇治疗进展
Clin Ophthalmol. 2016 Sep 8;10:1723-30. doi: 10.2147/OPTH.S115546. eCollection 2016.
2
Intraocular pressure elevation after intravitreal triamcinolone acetonide injection: a Meta-analysis.玻璃体内注射曲安奈德后眼压升高:一项Meta分析。
Int J Ophthalmol. 2016 Jan 18;9(1):139-44. doi: 10.18240/ijo.2016.01.23. eCollection 2016.
3
The Association between Intravitreal Steroids and Post-Injection Endophthalmitis Rates.玻璃体内注射类固醇与注射后眼内炎发生率之间的关联。
Ophthalmology. 2015 Nov;122(11):2311-2315.e1. doi: 10.1016/j.ophtha.2015.07.005. Epub 2015 Aug 15.
4
[Conspicuous crystalline lens foreign body after intravitreal injection].[玻璃体内注射后明显的晶状体异物]
Ophthalmologe. 2012 Nov;109(11):1119-21. doi: 10.1007/s00347-012-2650-8.
5
Incidence of damage to the crystalline lens during intravitreal injections.眼内注射时晶状体损伤的发生率。
J Ocul Pharmacol Ther. 2010 Oct;26(5):491-5. doi: 10.1089/jop.2010.0045.
6
Short-term complications of intravitreal injections of triamcinolone and bevacizumab.玻璃体内注射曲安奈德和贝伐单抗的短期并发症。
Eye (Lond). 2008 Apr;22(4):590-1. doi: 10.1038/eye.2008.10. Epub 2008 Feb 22.
7
Complications in patients after intravitreal injection of bevacizumab.玻璃体腔内注射贝伐单抗后患者的并发症。
Acta Ophthalmol. 2008 Jun;86(4):372-6. doi: 10.1111/j.1600-0420.2007.01067.x. Epub 2007 Nov 17.
8
The inadvertent administration of intralenticular triamcinolone.无意中给予晶状体内曲安奈德。
Eye (Lond). 2007 Mar;21(3):426-7. doi: 10.1038/sj.eye.6702658. Epub 2006 Dec 22.
9
Inadvertent injection of triamcinolone into the crystalline lens.曲安奈德意外注入晶状体。
Eye (Lond). 2007 Jan;21(1):152-4. doi: 10.1038/sj.eye.6702575. Epub 2006 Sep 1.
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Intravitreal triamcinolone acetonide in Eales disease.玻璃体内注射曲安奈德治疗伊尔斯病
Retina. 2006 Feb;26(2):227-9. doi: 10.1097/00006982-200602000-00020.