三氟甲磺酸二芳基碘𬭩盐的流动合成。
Flow Synthesis of Diaryliodonium Triflates.
机构信息
Department of Chemical Engineering and Chemistry, Micro Flow Chemistry & Process Technology, Eindhoven University of Technology , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
出版信息
J Org Chem. 2017 Nov 17;82(22):11735-11741. doi: 10.1021/acs.joc.7b01346. Epub 2017 Jul 20.
Abstract
A safe and scalable synthesis of diaryliodonium triflates was achieved using a practical continuous-flow design. A wide array of electron-rich to electron-deficient arenes could readily be transformed to their respective diaryliodonium salts on a gram scale, with residence times varying from 2 to 60 s (44 examples).
摘要
采用实用的连续流设计，实现了安全且可扩展的二芳基碘𬭩三氟甲磺酸酯的合成。通过这种方法，可以在克级规模上，很容易地将各种富电子到缺电子的芳烃转化为相应的二芳基碘𬭩盐，停留时间从 2 秒到 60 秒不等（44 个实例）。
Zotero 插件