Crul J F
Acta Anaesthesiol Belg. 1985 Dec;36(4):401-5.
The requirements for muscle relaxation in out-patient anesthesia are: a short total relaxation enabling the induction of an endotracheal tube followed by a period of 15-20 minutes of clinical relaxation. Reversal should be spontaneous. The new short acting muscle relaxants vecuronium and atracurium enable such a procedure, provided small doses are used (0.045 mg/kg for vecuronium or 0.2 mg/kg for atracurium. These small doses require a longer waiting time before intubation is easily performed (5 min for vecuronium and 6 min for atracurium). Spontaneous reversal of these small doses is achieved within 20-30 minutes. Potentiation of the relaxation by inhalational agents is not recommended.
完全松弛时间短,以便插入气管内导管,随后有15 - 20分钟的临床松弛期。恢复应是自发的。新型短效肌肉松弛剂维库溴铵和阿曲库铵能够实现这样的过程,前提是使用小剂量(维库溴铵0.045毫克/千克或阿曲库铵0.2毫克/千克)。这些小剂量在容易进行插管前需要更长的等待时间(维库溴铵5分钟,阿曲库铵6分钟)。这些小剂量在20 - 30分钟内可实现自发恢复。不建议使用吸入性药物增强松弛效果。