Berg K, Søli N E
Acta Vet Scand. 1985;26(3):363-73. doi: 10.1186/BF03546536.
Extracts of the blue-green alga Oscillatoria agardhii were tested for acute toxicity on laboratory mice and rats. Material originating from lake Gjersjøen proved to be toxic to the animals, samples from the nearby lake Årungen did not. Clinical symptoms culminated in the development of a fatal shock due to decrease in circulating blood volume. Pathological examination revealed heavy pooling of blood in the liver and severe damage to the organ. Blood analyses also indicated liver damage. Effects were the same with extracts from a laboratory clone culture as from a natural water bloom, but the toxin content was higher in the bloom material. Toxicity was not affected by heat, acid or alkali treatment.
对蓝绿藻颤藻提取物进行了实验室小鼠和大鼠的急性毒性测试。来自耶尔瑟湖的物质被证明对动物有毒，而附近阿伦湖的样本则无毒。临床症状最终发展为因循环血容量减少导致的致命休克。病理检查显示肝脏中血液大量淤积，器官严重受损。血液分析也表明肝脏受到损伤。实验室克隆培养物提取物与天然水华中提取物的效果相同，但水华物质中的毒素含量更高。毒性不受加热、酸或碱处理的影响。
