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颤藻毒素对血压及离体器官标本的影响。

Effects of Oscillatoria agardhii-toxins on blood pressure and isolated organ preparations.

作者信息

Berg K, Søli N E

出版信息

Acta Vet Scand. 1985;26(3):374-84. doi: 10.1186/BF03546537.

DOI:10.1186/BF03546537
PMID:3938183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8202708/
Abstract

Toxic extracts of the blue-green alga Oscillatoria agardhii were tested for their effect on various isolated laboratory animal preparations. The Oscillatoria-toxins did not show hemagglutinative or hemolytical properties. An immediate rise in blood pressure was seen after intravenous injection in rats. As regards isolated organs, effects were most marked on the liver. Addition of toxic extract to isolated liver perfusion fluid led to physiological, biochemical and pathological changes indicating severe damage to the organ. Negative chronotropic and inotropic effects were found on the isolated heart. The toxins did not influence isolated smooth muscle or nerve striated muscle preparations.

摘要

对蓝绿藻阿氏颤藻的有毒提取物进行了测试,以观察其对各种离体实验动物制剂的影响。颤藻毒素未表现出血凝或溶血特性。给大鼠静脉注射后,血压立即升高。至于离体器官,对肝脏的影响最为明显。向离体肝脏灌注液中添加有毒提取物会导致生理、生化和病理变化,表明该器官受到严重损害。在离体心脏上发现了负性变时和变力作用。毒素对离体平滑肌或神经横纹肌制剂没有影响。

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本文引用的文献

1
Microcystis aeruginosa toxin: cell culture toxicity, hemolysis, and mutagenicity assays.铜绿微囊藻毒素:细胞培养毒性、溶血及致突变性测定
Appl Environ Microbiol. 1982 Jun;43(6):1425-33. doi: 10.1128/aem.43.6.1425-1433.1982.
2
Hemagglutination method for detection of freshwater cyanobacteria (blue-green algae) toxins.用于检测淡水蓝藻(蓝绿藻)毒素的血凝法。
Appl Environ Microbiol. 1981 Jun;41(6):1383-8. doi: 10.1128/aem.41.6.1383-1388.1981.
3
Toxins of freshwater cyanobacteria.
Microbiol Sci. 1984 May;1(2):48-52.
4
A simple perfusion technique applied to glucocorticoid regulation of tryptophan oxygenase turnover and bile production in the isolated rat liver.一种简单的灌注技术应用于糖皮质激素对离体大鼠肝脏中色氨酸加氧酶周转和胆汁生成的调节。
Hoppe Seylers Z Physiol Chem. 1969 Mar;350(3):308-16. doi: 10.1515/bchm2.1969.350.1.308.
5
Toxicity studies with the blue-green alga Oscillatoria agardhii from two eutrophic Norwegian lakes.对来自挪威两个富营养化湖泊的蓝绿藻阿氏颤藻进行的毒性研究。
Acta Vet Scand. 1985;26(3):363-73. doi: 10.1186/BF03546536.