Doyle A E
Am J Cardiol. 1986 Feb 26;57(7):90D-92D. doi: 10.1016/0002-9149(86)90815-5.
The demonstration that antihypertensive drug treatment reduces mortality and morbidity in persons with mild hypertension has extended the indications for treatment. Verapamil, nitrendipine, angiotensin converting enzyme inhibitors and beta-adrenoceptor blocking drugs are equally effective in reducing blood pressure. The choice of which drug to use depends on the presence or absence of specific contraindications and the occurrence of adverse effects in the individual patient.
抗高血压药物治疗可降低轻度高血压患者的死亡率和发病率，这一事实已扩大了治疗指征。维拉帕米、尼群地平、血管紧张素转换酶抑制剂和β-肾上腺素受体阻断药在降低血压方面同样有效。选用哪种药物取决于个体患者是否存在特定禁忌证以及不良反应的发生情况。
