Creanga Andreea A, Syverson Carla, Seed Kristi, Callaghan William M
Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia; and the Department of International Health, Johns Hopkins Bloomberg School of Public Health, and the Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, Maryland.
Obstet Gynecol. 2017 Aug;130(2):366-373. doi: 10.1097/AOG.0000000000002114.
To update national population-level pregnancy-related mortality estimates and examine characteristics and causes of pregnancy-related deaths in the United States during 2011-2013.
We conducted an observational study using population-based data from the Pregnancy Mortality Surveillance System to calculate pregnancy-related mortality ratios by year, age group, and race-ethnicity groups. We explored 10 cause-of-death categories by pregnancy outcome during 2011-2013 and compared their distribution with those in our earlier reports since 1987.
The 2011-2013 pregnancy-related mortality ratio was 17.0 deaths per 100,000 live births. Pregnancy-related mortality ratios increased with maternal age, and racial-ethnic disparities persisted with non-Hispanic black women having a 3.4 times higher mortality ratio than non-Hispanic white women. Among causes of pregnancy-related deaths, the following groups contributed more than 10%: cardiovascular conditions ranked first (15.5%) followed by other medical conditions often reflecting pre-existing illnesses (14.5%), infection (12.7%), hemorrhage (11.4%), and cardiomyopathy (11.0%). Relative to the most recent report of Pregnancy Mortality Surveillance System data for 2006-2010, the distribution of cause-of-death categories did not change considerably. However, compared with serial reports before 2006-2010, the contribution of hemorrhage, hypertensive disorders of pregnancy, and anesthesia complications declined, whereas that of cardiovascular and other medical conditions increased (population-level percentage comparison).
The pregnancy-related mortality ratio and the distribution of the main causes of pregnancy-related mortality have been relatively stable in recent years.
更新全国人口水平的妊娠相关死亡估计数,并研究2011 - 2013年美国妊娠相关死亡的特征及原因。
我们利用妊娠死亡监测系统基于人群的数据进行了一项观察性研究,以按年份、年龄组和种族 - 族裔组计算妊娠相关死亡率。我们探讨了2011 - 2013年期间按妊娠结局划分的10个死因类别,并将其分布与我们自1987年以来的早期报告中的分布进行比较。
2011 - 2013年妊娠相关死亡率为每10万例活产中有17.0例死亡。妊娠相关死亡率随产妇年龄增加而上升,种族 - 族裔差异依然存在,非西班牙裔黑人女性的死亡率比非西班牙裔白人女性高3.4倍。在妊娠相关死亡原因中,以下类别占比超过10%:心血管疾病居首位(15.5%),其次是其他通常反映既往疾病的医疗状况(14.5%)、感染(12.7%)、出血(11.4%)和心肌病(11.0%)。相对于妊娠死亡监测系统2006 - 2010年数据的最新报告,死因类别的分布变化不大。然而,与2006 - 2010年之前的系列报告相比,出血、妊娠高血压疾病和麻醉并发症的占比下降,而心血管疾病和其他医疗状况的占比上升(人群水平百分比比较)。
近年来,妊娠相关死亡率及妊娠相关死亡主要原因的分布相对稳定。