Qiao Mingqi, Sun Peng, Wang Haijun, Wang Yang, Zhan Xianghong, Liu Hongqi, Wang Xiaoyun, Li Xia, Wang Xiaoru, Wu Jibiao, Wang Fushun
Key Laboratory of Traditional Chinese Medicine for Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
National Key Subject of TCM Psychology, State Administration of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Biomed Res Int. 2017;2017:4595016. doi: 10.1155/2017/4595016. Epub 2017 Jun 15.
We performed an epidemiological investigation of subjects with premenstrual dysphoric disorder (PMDD) to identify the clinical distribution of the major syndromes and symptoms. The pathogenesis of PMDD mainly involves the dysfunction of liver conveyance and dispersion. Excessive liver conveyance and dispersion are associated with liver-qi invasion syndrome, while insufficient liver conveyance and dispersion are expressed as liver-qi depression syndrome. Additionally, a nonconditional logistic regression was performed to analyze the symptomatic features of liver-qi invasion and liver-qi depression. As a result of this analysis, two subtypes of PMDD are proposed, namely, excessive liver conveyance and dispersion (liver-qi invasion syndrome) and insufficient liver conveyance and dispersion (liver-qi depression syndrome). Our findings provide an epidemiological foundation for the clinical diagnosis and treatment of PMDD based on the identification of different types.
我们对经前烦躁障碍（PMDD）患者进行了一项流行病学调查，以确定主要综合征和症状的临床分布。PMDD的发病机制主要涉及肝疏泄功能失调。肝疏泄太过与肝气侵袭证相关，而肝疏泄不及则表现为肝郁证。此外，进行了非条件逻辑回归分析以探讨肝气侵袭和肝郁的症状特征。基于该分析结果，提出了PMDD的两个亚型，即肝疏泄太过（肝气侵袭证）和肝疏泄不及（肝郁证）。我们的研究结果为基于不同类型识别的PMDD临床诊断和治疗提供了流行病学基础。
