Long T F, Edgecomb R S, Murdock L L
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1986;83(1):201-9. doi: 10.1016/0742-8413(86)90037-x.
The pharmacology of adult Phormia regina (Meigen) feeding behavior was explored by injecting candidate drugs into starved blowflies and then determining their responsiveness to aqueous sucrose, via the proboscis extension reflex. d-Amphetamine caused responsiveness to fall dramatically, while related drugs and biogenic amines had varying effects. When d-amphetamine-treated flies were fed 1 M sucrose, they consumed significantly more than control flies. Electrophysiological studies demonstrated that the responses of tarsal sugar receptor neurons to aqueous sucrose were not significantly altered by d-amphetamine. These observations are compatible with our hypothesis that octopamine positively modulates blowfly feeding behavior and suggest that other aromatic biogenic amines affect feeding behavior in this insect.
通过向饥饿的丽蝇注射候选药物，然后通过喙伸展反射测定它们对蔗糖水溶液的反应性，来探索成年黑尾麻蝇（Meigen）取食行为的药理学。d-苯丙胺导致反应性急剧下降，而相关药物和生物胺有不同的作用。当用d-苯丙胺处理的苍蝇喂食1M蔗糖时，它们的消耗量明显多于对照苍蝇。电生理学研究表明，跗节糖受体神经元对蔗糖水溶液的反应并没有因d-苯丙胺而发生显著改变。这些观察结果与我们的假设一致，即章鱼胺正向调节丽蝇的取食行为，并表明其他芳香族生物胺会影响这种昆虫的取食行为。
