Alentorn-Geli Eduard, Clark Nicholas J, Assenmacher Andrew T, Samuelsen Brian T, Sánchez-Sotelo Joaquín, Cofield Robert H, Sperling John W
Department of Orthopaedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Clin Orthop Relat Res. 2017 Nov;475(11):2744-2751. doi: 10.1007/s11999-017-5406-6. Epub 2017 Jul 11.
By the time patients with a failed shoulder arthroplasty require revision surgery, a substantial number are older than 80 years. The risk of complications of revision arthroplasty in this elderly population is largely unknown and needs to be considered when contemplating whether these patients are too frail for revision surgery.
QUESTIONS/PURPOSES: (1) What are the 90-day medical and surgical complications after revision to reverse shoulder arthroplasty (RSA) in patients older than 80 years? (2) What are the 2- and 5-year survival rates after revision? (3) Was there an improvement in pain at rest or with activity, range of motion (ROM), and strength after revision surgery?
Between 2004 and 2013, 38 patients who were older than 80 years (84 ± 3 years) underwent revision surgery to a RSA. Of those, five were lost to followup before 2 years, and two had died within 2 years of revision surgery, leaving 31 for analysis of our survivorship, pain, ROM, and strength endpoints at a minimum of 2 years or until revision surgery had occurred (mean, 28 months; range, 1-77 months); all 38 patients were included for purposes of evaluating medical and surgical complications at 90 days. During the period in question, our general indication for using RSA included failure of previous shoulder arthroplasty because of instability, glenoid loosening with bone loss, or rotator cuff insufficiency. The indication for revision to RSA did not change during the study period. The index procedure (revision to RSA at the age of 80 years or older) was the first revision arthroplasty in 33 (87%) patients and the second in five (13%) patients. We tallied 90-day medical and surgical complications by performing a retrospective chart and institutional joint registry review. The cumulative incidence of implant loosening (implant migration or tilting, or complete radiolucent lines present) and revision surgery was calculated at 2 and 5 years using competing risk of death method. Pain levels at rest or with activity (rated in a 1 to 5 Likert-type scale) were collected through a retrospective chart review and values before and after surgery were compared.
Medical complications occurred in three of 38 (8%) patients and surgical complications occurred in five of 38 (13%) patients. The 90-day mortality was 3% (one of 38 patients), and the total mortality was 26% (10 of 38 patients). The cumulative incidence of revision was 11% (95% CI, 0%-20%) at 2 years and 16% (95% CI, 1%-30%) at 5 years; the cumulative incidence of loosening was 8% (95% CI, 0%-20%) at 2 years and 16% (95% CI, 1%-30%) at 5 years. Pain at rest or with activity improved from pre- to postoperation (preoperative: median, 4 [range, 2-5]; postoperative: median, 1 [range, 1-4]; median difference: -2, 95% CI -3 to 0; p < 0.000). The active ROM improved during the preoperative compared with postoperative periods: mean ± SD forward flexion of 52° ± 40° to 109° ± 44°, respectively (mean difference: 56; 95% CI, 40-72; p < 0.000), and mean ± SD external rotation of 15° ± 22° to 31° ± 21°, respectively (mean difference: 16; 95% CI, 8-25; p < 0.000).
Age should not be used as a reason to not consider revision surgery to RSA in patients older than 80 years. Further studies with a prospective design, larger sample size, investigating risk factors for complications or poor outcome, and incorporation of functional scores are required.
Level IV, therapeutic study.
当肩关节置换失败的患者需要翻修手术时,相当一部分患者年龄超过80岁。在这一年龄较大的人群中,翻修关节成形术的并发症风险很大程度上未知,在考虑这些患者是否因身体过于虚弱而无法进行翻修手术时需要加以考虑。
问题/目的:(1)80岁以上患者翻转为反肩关节置换术(RSA)后的90天内科及外科并发症有哪些?(2)翻修后的2年和5年生存率是多少?(3)翻修手术后静息或活动时的疼痛、活动范围(ROM)和力量是否有所改善?
2004年至2013年期间,38例年龄超过80岁(84±3岁)的患者接受了RSA翻修手术。其中,5例在2年之前失访,2例在翻修手术后2年内死亡,剩余31例用于分析我们的生存、疼痛、ROM和力量终点,随访时间至少2年或直至进行翻修手术(平均28个月;范围1 - 77个月);所有38例患者均纳入90天内科及外科并发症评估。在所述期间,我们使用RSA的一般指征包括既往肩关节置换因不稳定、关节盂松动伴骨质丢失或肩袖功能不全而失败。在研究期间,翻转为RSA的指征未发生变化。索引手术(80岁及以上时翻转为RSA)是33例(87%)患者的首次翻修关节成形术,5例(13%)患者的第二次翻修关节成形术。我们通过回顾病历和机构关节登记处进行回顾,统计90天内科及外科并发症。采用竞争风险死亡法计算2年和5年时植入物松动(植入物移位或倾斜,或出现完全透亮线)和翻修手术的累积发生率。通过回顾病历收集静息或活动时的疼痛水平(采用1至5分的李克特量表评分),并比较手术前后的值。
38例患者中有3例(8%)发生内科并发症,38例患者中有5例(13%)发生外科并发症。90天死亡率为3%(38例患者中的1例),总死亡率为26%(38例患者中的10例)。翻修的累积发生率在2年时为11%(95%CI,0% - 20%),5年时为16%(95%CI,1% - 30%);松动的累积发生率在2年时为8%(95%CI,0% - 20%),5年时为16%(95%CI,1% - 30%)。静息或活动时的疼痛从术前到术后有所改善(术前:中位数为4[范围2 - 5];术后:中位数为1[范围1 - 4];中位数差值: - 2,95%CI - 3至0;p < 0.000)。与术前相比,主动ROM在术后有所改善:前屈平均±标准差分别从52°±40°提高到109°±44°(平均差值:56;95%CI,40 - 72;p < 0.000),外旋平均±标准差分别从15°±22°提高到31°±21°(平均差值:16;95%CI,8 - 25;p < 0.000)。
年龄不应作为不考虑对80岁以上患者进行RSA翻修手术的理由。需要进行前瞻性设计、更大样本量、研究并发症或不良结局危险因素以及纳入功能评分的进一步研究。
IV级,治疗性研究。