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Dogfish metallothionein--I. Purification and characterization and comparison with rat metallothionein.

作者信息

Hidalgo J, Flos R

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1986;83(1):99-103. doi: 10.1016/0742-8413(86)90019-8.

DOI:10.1016/0742-8413(86)90019-8
PMID:2869915
Abstract

A low-molecular weight metal-binding protein has been found in the liver of the dogfish (Scyliorhinus canicula) in both control and cadmium-treated animals and in both male and female animals. This protein is present as Zn, Cu-protein in control and as Cd, Zn, Cu-protein cadmium-treated (both water and i.p. administration) animals. This hepatic protein was characterized as metallothionein from several properties related to mammalian metallothionein. A different response to cadmium administration between sexes is suggested.

摘要

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