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基于学术中心病例数量的老年人群头颈癌手术结果。

Outcomes of head and neck cancer surgery in the geriatric population based on case volume at academic centers.

作者信息

Jalisi Scharukh, Rubin Samuel J, Wu Kevin Y, Kirke Diana N

机构信息

Department of Otolaryngology-Head and Neck Surgery, Boston Medical Center, Boston, Massachusetts, U.S.A.

出版信息

Laryngoscope. 2017 Nov;127(11):2539-2544. doi: 10.1002/lary.26750. Epub 2017 Jul 12.

Abstract

OBJECTIVES/HYPOTHESIS: Evaluate the impact of case volume and other variables on cost and mortality after head and neck oncologic surgery in the geriatric population.

STUDY DESIGN

Cross-sectional study.

METHODS

The Vizient database was accessed for data on geriatric patients (age ≥65 years) who underwent surgery for head and neck cancers (excluding thyroid and skin cancer) at full member academic medical centers between 2009 and 2012. Multivariate, linear regression analyses, χ tests, and analysis of variance were applied to evaluate significant associations between hospital case volume and independent variables including cost, cost index, mortality, mortality index, length of stay, length of stay index, and readmission rates.

RESULTS

A total of 4,544 patients were included. Total length of stay was 6.72 days in high-volume hospitals, compared to 8.12 days and 7.91 days in moderate- and low-volume hospitals, respectively (P = .0144). Frequency of intensive care unit stays was 36.5% in high-volume hospitals, compared to 42.19% and 40.29% in moderate- and low-volume hospitals, respectively (P = .0048). Mortality (0.78%) and average cost per case ($21,834) was lower, but nonsignificant in high-volume hospitals. Using multiple regression analysis, major severity of disease was positively associated with complication rate (P < .0001) and length of stay (P = .0481).

CONCLUSIONS

After controlling for other factors, high-volume academic medical centers have a lower intensive care unit stay, but no difference in mortality or average cost per case when compared to low-volume hospitals.

LEVEL OF EVIDENCE

2b. Laryngoscope, 127:2539-2544, 2017.

摘要

目的/假设:评估病例数量及其他变量对老年人群头颈部肿瘤手术后成本和死亡率的影响。

研究设计

横断面研究。

方法

访问Vizient数据库,获取2009年至2012年间在成员学术医疗中心接受头颈部癌症(不包括甲状腺癌和皮肤癌)手术的老年患者(年龄≥65岁)的数据。应用多变量线性回归分析、χ检验和方差分析,以评估医院病例数量与包括成本、成本指数、死亡率、死亡指数、住院时间、住院时间指数和再入院率在内的自变量之间的显著关联。

结果

共纳入4544例患者。高容量医院的总住院时间为6.72天,而中等容量医院和低容量医院分别为8.12天和7.91天(P = 0.0144)。高容量医院重症监护病房住院频率为36.5%,中等容量医院和低容量医院分别为42.19%和40.29%(P = 0.0048)。高容量医院的死亡率(0.78%)和每例平均成本(21,834美元)较低,但无显著差异。使用多元回归分析,疾病的主要严重程度与并发症发生率(P < 0.0001)和住院时间(P = 0.0481)呈正相关。

结论

在控制其他因素后,与低容量医院相比,高容量学术医疗中心的重症监护病房住院时间较短,但死亡率或每例平均成本无差异。

证据水平

2b。《喉镜》,2017年,第127卷,第2539 - 2544页。

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