Hong Shuhui, Cui Jing, Li Li, Buscema Joseph, Liggins Casandra, Zheng Wenxin
Departments of Gynecology (S.H.) Pathology (J.C.), Shandong Provincial Qianfoshan Hospital Department of Pathology, School of Medicine (L.L.), Shandong University, Jinan, Shandong, China Arizona Oncology Associates, Tucson, Arizona (J.B., C.L.) Departments of Pathology (S.H., J.C., L.L., W.Z.) Obstetrics and Gynecology (W.Z.), University of Texas Southwestern Medical Center Harold C. Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center (W.Z.), Dallas, Texas.
Int J Gynecol Pathol. 2018 Jul;37(4):331-337. doi: 10.1097/PGP.0000000000000422.
Although most female adnexal tumors of probable Wolffian origin have a benign biologic behavior, occasional cases have exhibited malignant potential. We encountered a 50-yr-old woman with an uncommon female adnexal tumors of probable Wolffian origin, which involved bilateral ovaries, invaded the ipsilateral fallopian tube, and extended to the uterine serosa. The initial histopathologic presentation caused significant confusion in pathologic diagnosis. Multiple differential diagnoses including ovarian endometrioid carcinoma, Sertoli cell tumor, and metastasis from nongynecologic organs were considered. After careful examination of the histologic findings and a thorough investigation with multiple immunohistochemical stains, the diagnosis was ultimately established. A literature review on female adnexal tumors of probable Wolffian origin including a malignant form is presented.
尽管大多数可能起源于中肾管的女性附件肿瘤具有良性生物学行为，但偶尔也有病例表现出恶性潜能。我们遇到一名50岁女性，患有一种罕见的可能起源于中肾管的女性附件肿瘤，该肿瘤累及双侧卵巢，侵犯同侧输卵管，并蔓延至子宫浆膜层。最初的组织病理学表现给病理诊断带来了很大困惑。考虑了多种鉴别诊断，包括卵巢子宫内膜样癌、支持细胞瘤以及非妇科器官转移瘤。经过对组织学结果的仔细检查和多次免疫组化染色的全面研究，最终确立了诊断。本文还对包括恶性形式在内的可能起源于中肾管的女性附件肿瘤进行了文献综述。
