Huang Ling, Zhou Yan, Hong Xiaoshan, Luo Xiping, Shen Min, Yan Shanshan, Sun Xiaoli
Department of Gynaecology, Guangdong Women and Children Hospital, Guangzhou, China.
Department of Radiology, Guangdong Women and Children Hospital, Guangzhou, China.
Cancer Rep (Hoboken). 2024 Dec;7(12):e70084. doi: 10.1002/cnr2.70084.
Wolffian adnexal tumor is a rare type of tumor that was first discovered and reported by Karim-inejad in 1973. Wolffian adnexal tumor lacks specific clinical manifestations and its histological morphology is similar to various other tumors, making it highly prone to misdiagnosis. To enhance our understanding of this disease, we hereby report a case of Wolffian adnexal tumor diagnosed and treated in our hospital.
It is the first report of a giant bilateral Wolffian tumor, with pleural effusion and pericardial effusion as the initial symptoms. Magnetic resonance imaging (MRI) suggested a huge lobulated mass (25.3 × 17.8 × 21.9 cm) in the mid-lower abdomen and pelvis, involving both ovaries. A diagnosis of "ovarian malignancy" was made before the surgery. Hysterectomy, bilateral adnexectomy, and omentectomy were performed. Postoperative pathology revealed a bilateral Wolffian tumor. Postoperative chemotherapy with a taxol and cisplatin (TP) regimen was administered for six cycles. Follow-up at 2 months postoperatively showed resolution of pericardial and pleural effusions, and there has been no recurrence during the 3-year follow-up period.
Wolffian adnexal tumor lacks specific clinical manifestations, and its prognosis is good after treatment.
中肾旁管附属器肿瘤是一种罕见的肿瘤类型，于1973年由卡里姆 - 伊内贾德首次发现并报道。中肾旁管附属器肿瘤缺乏特异性临床表现，其组织形态学与其他多种肿瘤相似，极易误诊。为提高我们对该疾病的认识，我们在此报告我院诊断和治疗的一例中肾旁管附属器肿瘤病例。
这是首例以胸腔积液和心包积液为首发症状的双侧巨大中肾旁管肿瘤的报告。磁共振成像（MRI）显示中下腹部及盆腔有一巨大分叶状肿块（25.3×17.8×21.9 cm），累及双侧卵巢。术前诊断为“卵巢恶性肿瘤”。行子宫切除术、双侧附件切除术及大网膜切除术。术后病理显示为双侧中肾旁管肿瘤。术后采用紫杉醇和顺铂（TP）方案化疗6个周期。术后2个月随访显示心包积液和胸腔积液消退，在3年随访期内无复发。
中肾旁管附属器肿瘤缺乏特异性临床表现，治疗后预后良好。
