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产前诊断：先天性高位气道梗阻。

An antenatal diagnosis: Congenital high airway obstruction.

作者信息

Miital S, Mittal A, Singal R, Singal S, Sekhon G

机构信息

Department of Radiodiagnosis and Imaging, M.M. Institute of Medical Sciences and Research, Mullana, Haryana, India.

Department of Surgery, M.M. Institute of Medical Sciences and Research, Mullana, Haryana, India.

出版信息

Ann Card Anaesth. 2017 Jul-Sep;20(3):335-336. doi: 10.4103/0971-9784.210407.

DOI:10.4103/0971-9784.210407
PMID:28701601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5535577/
Abstract

Congenital high airway obstruction (CHAOS) is a rare lethal fetal malformation characterised by obstruction to the fetal upper airway, which can be partial or complete. Antenatal diagnosis of CHAOS is important due to recent management options. Diagnosis is made with secondary changes such as hyperechoic enlarged lungs resulting in mediastinal compression, ascites, hydrops, flattened or everted diaphragms and dilated distal airways. We reported a case of CHAOS, antenatally on ultrasonography (USG) at 20 weeks of gestation.

摘要

先天性高位气道梗阻（CHAOS）是一种罕见的致死性胎儿畸形，其特征为胎儿上呼吸道梗阻，可为部分性或完全性。由于近期的治疗选择，CHAOS的产前诊断很重要。诊断依据继发改变做出，如肺回声增强增大导致纵隔受压、腹水、水肿、膈肌扁平或翻转以及远端气道扩张。我们报告了1例妊娠20周时经超声检查（USG）产前诊断为CHAOS的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e80/5535577/2061aa89c8f9/ACA-20-335-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e80/5535577/e3b212144489/ACA-20-335-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e80/5535577/f49cb0d2d8ba/ACA-20-335-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e80/5535577/2061aa89c8f9/ACA-20-335-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e80/5535577/e3b212144489/ACA-20-335-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e80/5535577/f49cb0d2d8ba/ACA-20-335-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e80/5535577/2061aa89c8f9/ACA-20-335-g003.jpg

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Congenital high airway obstruction with tracheoesophageal fistula: A case report.先天性高位气道梗阻合并气管食管瘘：一例报告。
Medicine (Baltimore). 2018 Dec;97(51):e13709. doi: 10.1097/MD.0000000000013709.

本文引用的文献

1
Prenatal diagnosis of congenital high airway obstruction syndrome (CHAOS). Five case report.先天性高气道梗阻综合征（CHAOS）的产前诊断。五例报告。
Med Ultrason. 2015 Mar;17(1):115-8. doi: 10.11152/mu.2013.2066.171.haek.
2
Prenatal diagnosis of congenital high airway obstruction syndrome: report of two cases and brief review of the literature.先天性高位气道梗阻综合征的产前诊断：两例报告并文献简要回顾
Case Rep Obstet Gynecol. 2013;2013:728974. doi: 10.1155/2013/728974. Epub 2013 Oct 22.
3
Omphalocele and gastroschisis associated with multiple congenital abnormalities.
脐膨出和腹裂合并多种先天性畸形。
J Med Life. 2011 Aug 15;4(3):295-6. Epub 2011 Aug 25.