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一名患有扩张型心肌病和副肿瘤性共济失调的男性的霍奇金淋巴瘤：治疗挑战

Hodgkin's Lymphoma in a Man with Dilated Cardiomyopathy and Paraneoplastic Ataxia: A Therapeutical Challenge.

作者信息

Abruzzese Elisabetta, Trawinska Malgorzata Monika, Gaspardone Achille, Morocutti Antonino, de Fabritiis Paolo

机构信息

Division of Hematology, S. Eugenio Hospital, Tor Vergata University, Rome, Italy.

Division of Cardiology, S. Eugenio Hospital, Tor Vergata University, Rome, Italy.

出版信息

Hematol Rep. 2017 Jun 28;9(2):6944. doi: 10.4081/hr.2017.6944. eCollection 2017 Jun 1.

DOI:10.4081/hr.2017.6944
PMID:28702159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5494442/
Abstract

Hodgkin's lymphoma is a cancer of the lymphatic system. We report the case of a man with Hodgkin's lymphoma and cardiomyopathy, for which the dilemma was whether to use the standard protocol - putting the patient at risk of worsening of heart failure, but giving him a good chance of full recovery - or not. The standard protocol was given and the patient made a full recovery without cardiac complications.

摘要

霍奇金淋巴瘤是一种淋巴系统癌症。我们报告了一例患有霍奇金淋巴瘤和心肌病的男性病例，面临的两难困境是是否采用标准治疗方案——这会使患者有心力衰竭恶化的风险，但能给他完全康复的良好机会——还是不采用。最终采用了标准治疗方案，患者完全康复且未出现心脏并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c08a/5494442/2920cf857296/hr-9-2-6944-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c08a/5494442/2920cf857296/hr-9-2-6944-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c08a/5494442/2920cf857296/hr-9-2-6944-g001.jpg

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本文引用的文献

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Biweekly rituximab, cyclophosphamide, vincristine, non-pegylated liposome-encapsulated doxorubicin and prednisone (R-COMP-14) in elderly patients with poor-risk diffuse large B-cell lymphoma and moderate to high 'life threat' impact cardiopathy.每周两次利妥昔单抗、环磷酰胺、长春新碱、非聚乙二醇化脂质体阿霉素和泼尼松（R-COMP-14）治疗老年高危弥漫性大 B 细胞淋巴瘤和中高危“生命威胁”型心肌病患者。
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Classical Hodgkin's lymphoma in adults: guidelines of the Italian Society of Hematology, the Italian Society of Experimental Hematology, and the Italian Group for Bone Marrow Transplantation on initial work-up, management, and follow-up.成人经典型霍奇金淋巴瘤：意大利血液学会、意大利实验血液学会及意大利骨髓移植组关于初始检查、管理及随访的指南
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Doxorubicin, cardiac risk factors, and cardiac toxicity in elderly patients with diffuse B-cell non-Hodgkin's lymphoma.多柔比星、心脏危险因素与老年弥漫性B细胞非霍奇金淋巴瘤患者的心脏毒性
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Liposome-encapsulated doxorubicin in combination with cyclophosphamide, vincristine, prednisone and rituximab in patients with lymphoma and concurrent cardiac diseases or pre-treated with anthracyclines.脂质体包裹的阿霉素联合环磷酰胺、长春新碱、泼尼松和利妥昔单抗用于患有淋巴瘤且合并心脏疾病或曾接受蒽环类药物预处理的患者。
Hematol Oncol. 2007 Dec;25(4):198-203. doi: 10.1002/hon.827.
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Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease: Cotswolds meeting.关于召集讨论霍奇金病患者评估与分期的委员会报告：科茨沃尔德会议
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