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采用国际糖尿病与妊娠研究组(IADPSG)和世界卫生组织1999年标准(WINGS 6)评估泰米尔纳德邦城乡地区妊娠糖尿病的患病率。

Prevalence of Gestational Diabetes Mellitus in urban and rural Tamil Nadu using IADPSG and WHO 1999 criteria (WINGS 6).

作者信息

Bhavadharini Balaji, Mahalakshmi Manni Mohanraj, Anjana Ranjit Mohan, Maheswari Kumar, Uma Ram, Deepa Mohan, Unnikrishnan Ranjit, Ranjani Harish, Pastakia Sonak D, Kayal Arivudainambi, Ninov Lyudmil, Malanda Belma, Belton Anne, Mohan Viswanathan

机构信息

Madras Diabetes Research Foundation, 4, Conran Smith Road, Gopalapuram, Chennai, 600 086 India.

Seethapathy Clinic and Hospital, Chennai, India.

出版信息

Clin Diabetes Endocrinol. 2016 Apr 5;2:8. doi: 10.1186/s40842-016-0028-6. eCollection 2016.

Abstract

BACKGROUND

To determine the prevalence of Gestational Diabetes Mellitus (GDM) in urban and rural Tamil Nadu in southern India, using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) and the World Health Organization (WHO) 1999 criteria for GDM.

METHODS

A total of 2121 pregnant women were screened for GDM from antenatal clinics in government primary health centres of Kancheepuram district ( = 520) and private maternity centres in Chennai city in Tamil Nadu ( = 1601) between January 2013 to December 2014. Oral glucose tolerance tests (OGTT) were done after an overnight fast of at least 8 h, using a 75 g glucose load and venous samples were drawn at 0, 1 and 2 h. GDM was diagnosed using both the IADPSG criteria as well as the WHO 1999 criteria for GDM.

RESULTS

The overall prevalence of GDM after adjusting for age, BMI, family history of diabetes and previous history of GDM was 18.5 % by IADPSG criteria with no significant urban/rural differences (urban 19.8 % vs rural 16.1 %,  = 0.46). Using the WHO 1999 criteria, the overall adjusted prevalence of GDM was 14.6 % again with no significant urban/rural differences (urban 15.9 % vs rural 8.9 %,  = 0.13).

CONCLUSION

The prevalence of GDM by IADPSG was high both using IADPSG as well as WHO 1999 criteria with no significant urban/rural differences. This emphasizes the need for increasing awareness about GDM and for prevention of GDM in developing countries like India.

摘要

背景

采用国际糖尿病与妊娠研究组(IADPSG)和世界卫生组织(WHO)1999年妊娠期糖尿病(GDM)诊断标准,确定印度南部泰米尔纳德邦城乡地区GDM的患病率。

方法

2013年1月至2014年12月期间,对金奈市(1601例)和坎契普尔姆区政府初级卫生中心(520例)产前诊所的2121名孕妇进行GDM筛查。口服葡萄糖耐量试验(OGTT)在至少禁食8小时后进行,采用75克葡萄糖负荷,分别于0、1和2小时采集静脉血样。采用IADPSG标准和WHO 1999年GDM诊断标准进行诊断。

结果

校正年龄、体重指数、糖尿病家族史和既往GDM史后,根据IADPSG标准,GDM总体患病率为18.5%,城乡之间无显著差异(城市19.8%,农村16.1%,P = 0.46)。根据WHO 1999年标准,校正后GDM总体患病率为14.6%,城乡之间同样无显著差异(城市15.9%vs农村8.9%,P = 0.13)。

结论

根据IADPSG标准以及WHO 1999年标准,GDM患病率均较高,城乡之间无显著差异。这凸显了在印度等发展中国家提高对GDM的认识并预防GDM的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef3/5471800/d6ad01504697/40842_2016_28_Fig1_HTML.jpg

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