Zerbinati N, Haddad R G, Bader A, Rauso R, D'Este E, Cipolla G, Calligaro A, Gonzalez P, Salvatore S, Serafin D
Department of Surgical and Morphological Sciences, University of Insubria (Varese), Italy.
Consultant Obstetric Gynecology Faculty of the American Academy Aesthetic Gynecology Dubai - Paris – Riyadh.
J Biol Regul Homeost Agents. 2017;31(2 Suppl. 2):153-161.
Aesthetic surgery of female external genitalia has gained increasing popularity over the past decade, with reduction of the labia minora (labiaplasty) being the procedure most commonly requested and performed. Female external genitalia lose elasticity and volume with age, but few studies describe the techniques for labia majora augmentation. Currently, very few studies have investigated the effectiveness and safety of labia majora augmentation with hyaluronic acid (HA) injection. This study aims to evaluate the effectiveness and safety of labia majora augmentation with hyaluronic acid filler injection. We retrospectively analyzed 37 patients affected by hypotrophy of the labia majora, treated with HA dermal filler 28mg/ml PEG crosslinked (Neauvia® Intense Rose, Matex Lab, Switzerland) between May 2015 and July 2016. Global evaluation of the aesthetics of the intimate area and clinical data were investigated with VAS (Visual Analogic Scale) ad hoc. Adverse events and complications were recorded. A total of 37 women affected by labia majora hypotrophy were treated with 28mg/ml HA dermal filler. A significant clinical improvement was observed in the score provided by both patients and doctor. Only mild adverse events and complications were recorded. HA hydrogel with a novel crosslinking agent is able to provide a considerable rejuvenation with a simple outpatient procedure and to bring a significant clinical improvement. HA-based filler infiltration treatment in labia majora is repeatable, has virtually no complications, and is reversible.
在过去十年中，女性外生殖器美容手术越来越受欢迎，其中小阴唇缩小术（阴唇整形术）是最常被要求实施的手术。女性外生殖器会随着年龄增长而失去弹性和体积，但很少有研究描述大阴唇增大的技术。目前，很少有研究调查透明质酸（HA）注射用于大阴唇增大的有效性和安全性。本研究旨在评估透明质酸填充剂注射用于大阴唇增大的有效性和安全性。我们回顾性分析了2015年5月至2016年7月期间37例受大阴唇萎缩影响的患者，她们接受了28mg/ml聚乙二醇交联的透明质酸真皮填充剂（Neauvia® Intense Rose，瑞士马特克斯实验室）治疗。使用专门的视觉模拟量表（VAS）对私密部位美学进行整体评估并调查临床数据。记录不良事件和并发症。共有37例受大阴唇萎缩影响的女性接受了28mg/ml透明质酸真皮填充剂治疗。患者和医生给出的评分均显示出显著的临床改善。仅记录到轻微的不良事件和并发症。含有新型交联剂的透明质酸水凝胶能够通过简单的门诊手术实现显著的年轻化，并带来显著的临床改善。基于透明质酸的填充剂浸润治疗大阴唇具有可重复性，几乎没有并发症，且是可逆的。
