Adam Vojtech, Vaculovicova Marketa
Department of Chemistry and Biochemistry, Mendel University in Brno, Brno, Czech Republic.
Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic.
Electrophoresis. 2017 Oct;38(19):2405-2430. doi: 10.1002/elps.201700098. Epub 2017 Aug 31.
The scope of this two-part review is to summarize publications dealing with CE and nanomaterials together. This topic can be viewed from two broad perspectives, and this article is trying to highlight these two approaches: (i) CE of nanomaterials, and (ii) nanomaterials in CE. The second part aims at summarization of publications dealing with application of nanomaterials for enhancement of CE performance either in terms of increasing the separation resolution or for improvement of the detection. To increase the resolution, nanomaterials are employed as either surface modification of the capillary wall forming open tubular column or as additives to the separation electrolyte resulting in a pseudostationary phase. Moreover, nanomaterials have proven to be very beneficial for increasing also the sensitivity of detection employed in CE or even they enable the detection (e.g., fluorescent tags of nonfluorescent molecules).
这篇分为两部分的综述旨在总结有关毛细管电泳（CE）和纳米材料的相关出版物。该主题可从两个广泛的角度来看待，本文试图突出这两种方法：（i）纳米材料的毛细管电泳，以及（ii）毛细管电泳中的纳米材料。第二部分旨在总结有关纳米材料应用的出版物，这些应用旨在通过提高分离分辨率或改善检测来增强毛细管电泳性能。为了提高分辨率，纳米材料可用于对毛细管内壁进行表面修饰以形成开管柱，或作为分离电解质的添加剂以形成假固定相。此外，纳米材料已被证明对于提高毛细管电泳中的检测灵敏度也非常有益，甚至它们还能实现检测（例如，对非荧光分子进行荧光标记）。
