Chao A-Ching, Han Ke, Chang Feng-Chi, Hsu Hung-Yi, Chung Chih-Ping, Sheng Wen-Yung, Chan Lung, Wu Jiang, Hu Han-Hwa
Department of Neurology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
PLoS One. 2017 Jul 13;12(7):e0181119. doi: 10.1371/journal.pone.0181119. eCollection 2017.
Accurate diagnosis of subtypes of transverse sinus (TS) hypoplasia requires more expensive methods like magnetic resonance (MR) imaging. We hypothesized ultrasound findings of the internal jugular vein (IJV) can be surrogate indicators for diagnosis of TS hypoplasia. MR images were reviewed in 131 subjects to evaluate TS diameter and the location and degree of venous flow stenosis and obstruction. Ultrasound parameters including the cross-sectional lumen area (CSA), time-average-mean velocity (TAMV), and flow volume (FV) at each IJV segment were also evaluated. Sixty-nine subjects had TS hypoplasia based on MRV criteria, of which 39 TS hypoplasia were considered a subtype of TS hypoplasia, which is secondary to the downstream venous compression/stenosis or left brachiocephalic vein. In the ultrasound study, the CSA of the IJV ipsilateral to TS hypoplasia was significantly smaller. Further, a contralateral/ipsilateral IJV CSA ratio >1.55 provided good sensitivity, specificity, and positive predictive value for discriminating TS hypoplasia.
准确诊断横窦（TS）发育不全的亚型需要采用如磁共振成像（MR）等更昂贵的方法。我们推测颈内静脉（IJV）的超声检查结果可作为诊断TS发育不全的替代指标。对131名受试者的MR图像进行了回顾，以评估TS直径以及静脉血流狭窄和阻塞的位置与程度。还评估了每个IJV节段的超声参数，包括横截面积（CSA）、时间平均平均速度（TAMV）和血流量（FV）。根据MRV标准，69名受试者存在TS发育不全，其中39例TS发育不全被认为是TS发育不全的一种亚型，其继发于下游静脉压迫/狭窄或左头臂静脉。在超声研究中，TS发育不全同侧的IJV的CSA显著更小。此外，对侧/同侧IJV CSA比值>1.55对鉴别TS发育不全具有良好的敏感性、特异性和阳性预测值。
