Nowak J Z
Pol J Pharmacol Pharm. 1985 Nov-Dec;37(6):783-819.
This paper presents and summarizes our recent results on histamine (HI) in vertebrate visual system. The data include: 1. HI distribution, localization, synthesis, uptake and metabolism in retina, optic nerve, choroid and brain of carp, hen, rabbit, cow, 2. distribution of HI in human eyes, 3. 3H-mepyramine binding in the bovine retina, and HI dependent cAMP generating system in the rabbit eye, 4. effect of light stimulation on HI content in the rabbit retina, optic nerve and brain, 5. diurnal variations of histidine decarboxylase and histamine-methyltransferase activity in the rabbit ocular and brain structures. These results are discussed in terms of possible function(s) of HI in the visual system.
本文展示并总结了我们近期在脊椎动物视觉系统中关于组胺（HI）的研究成果。数据包括：1. 鲤鱼、母鸡、兔子、牛的视网膜、视神经、脉络膜和大脑中HI的分布、定位、合成、摄取及代谢；2. HI在人眼中的分布；3. 牛视网膜中3H-美吡拉敏结合情况以及兔眼中HI依赖的环磷酸腺苷生成系统；4. 光刺激对兔视网膜、视神经和大脑中HI含量的影响；5. 兔眼和脑结构中组氨酸脱羧酶和组胺甲基转移酶活性的昼夜变化。本文依据HI在视觉系统中可能的功能对这些结果进行了讨论。
