1 Department of Psychology, Ryerson University, Toronto, Ontario, Canada.
2 Division of Geriatric Psychiatry, Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Am J Alzheimers Dis Other Demen. 2017 Nov;32(7):393-400. doi: 10.1177/1533317517718954. Epub 2017 Jul 13.
To examine the nature and frequency of cognitive fluctuations (CFs) among institutionalized persons with dementia.
A clinical interview and a medical chart review were conducted, and 55 patients were assigned a specific dementia diagnosis. The Severe Impairment Battery (SIB) was administered to assess cognitive function, and the Dementia Cognitive Fluctuation Scale (DCFS) was administered to each patient's primary nurse to determine the presence and severity of CFs.
A simple linear regression model was conducted with DCFS as the predictor variable and SIB total score as the dependent variable. The overall model was significant, suggesting that score on the DCFS significantly predicted SIB total score. Additionally, greater severity of CFs predicted poorer performance in the areas of orientation, language, and praxis.
Results suggest that CFs exert a clinically significant influence over patients' cognitive abilities and should be considered as a source of excess disability.
研究机构内痴呆患者认知波动(CFs)的性质和频率。
进行临床访谈和病历回顾,对 55 名患者进行特定的痴呆诊断。采用严重损伤量表(SIB)评估认知功能,对每位患者的主管护士采用痴呆认知波动量表(DCFS)确定 CFs 的存在和严重程度。
以 DCFS 为预测变量,SIB 总分作为因变量进行简单线性回归模型。整体模型具有统计学意义,表明 DCFS 的评分显著预测了 SIB 总分。此外,CFs 的严重程度与定向、语言和实践领域的表现更差相关。
结果表明,CFs 对患者的认知能力有显著的临床影响,应将其视为额外残疾的来源。