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转座元件的群体生物学

The population biology of transposable elements.

作者信息

Brookfield J F

出版信息

Philos Trans R Soc Lond B Biol Sci. 1986 Jan 29;312(1154):217-26. doi: 10.1098/rstb.1986.0003.

Abstract

A transposable element can be defined as a DNA sequence capable of moving to new sites in the genome. Such DNA sequences have been described in a wide range of organisms. The evolutionary processes affecting transposable elements can thus be divided into two categories: changes in sequence and changes in genomic location. As with other types of evolutionary change, the nature of the evolutionary process will be reflected in the extent and type of genetic variation existing in wild populations. Quantitative models of the evolution of transposable element sequences and positions will be outlined, and related to relevant data. The extent to which models designed to describe obvious transposable elements such as the mobile sequences of Drosophila are also applicable to interspersed repetitive DNAs from other species will be discussed.

摘要

转座元件可定义为一种能够移动到基因组新位点的DNA序列。此类DNA序列已在多种生物中得到描述。因此,影响转座元件的进化过程可分为两类:序列变化和基因组位置变化。与其他类型的进化变化一样,进化过程的性质将反映在野生种群中存在的遗传变异的程度和类型上。将概述转座元件序列和位置进化的定量模型,并与相关数据相关联。还将讨论旨在描述明显转座元件(例如果蝇的移动序列)的模型在何种程度上也适用于其他物种的散布重复DNA。

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