中东地区自身免疫性大疱性疾病谱：一项15年的回顾

Spectrum of Autoimmune Bullous Diseases in the Middle East: A 15-Year Review.

作者信息

Haber Roger, Helou Josiane, Habr Carla, Tomb Roland

机构信息

Department of Dermatology, Saint George Hospital University Medical Center, Balamand Faculty of Medicine, Achrafieh, Beirut, Lebanon, Hôtel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon;

Department of Dermatology, Hôtel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.

出版信息

Skinmed. 2017 Jun 1;15(3):181-186. eCollection 2017.

PMID:28705277

Abstract

Characteristics of autoimmune bullous diseases (AIBDs) show wide geographic variation. The aim of this study was to determine retrospectively the characteristics of patients with AIBD admitted to Hôtel-Dieu de France Hospital in Beirut, Lebanon, between 1999 and 2014 and to compare them with those from other areas in the Middle East, the Far East, Asia, North Africa, Europe, and North America. For the patients with AIBDs and who were hospitalized at a major tertiary referral center between 1999 and 2004, we studied demographics, diagnosis, length of stay, department/floor, comorbidities, clinical features, in-hospital evolution, diagnostic tests, and treatment. Bullous pemphigoides was the most frequent bullous disease in Lebanon. This and other findings contrast with those of studies conducted in regional countries. This is the first report of AIBD from the Middle Eastern region.

摘要

自身免疫性大疱性疾病（AIBDs）的特征存在广泛的地域差异。本研究的目的是回顾性确定1999年至2014年间在黎巴嫩贝鲁特法国医院（Hôtel-Dieu de France Hospital）住院的AIBD患者的特征，并将其与中东、远东、亚洲、北非、欧洲和北美的其他地区的患者特征进行比较。对于1999年至2004年间在一家大型三级转诊中心住院的AIBD患者，我们研究了人口统计学、诊断、住院时间、科室/楼层、合并症、临床特征、住院期间病情演变、诊断测试和治疗情况。大疱性类天疱疮是黎巴嫩最常见的大疱性疾病。这一发现以及其他发现与该地区国家开展的研究结果形成对比。这是中东地区关于AIBD的首份报告。