Konikova R E, Stepanov A V, Sviridov L P
Zh Mikrobiol Epidemiol Immunobiol. 1986 Feb(2):81-4.
Experiments on 575 noninbred white mice have revealed that the nonspecific resistance of the animals to type A C. perfringens toxin can be enhanced by the administration of Prodigiosan, a commercial immunostimulating agent. Prodigiosan, introduced in 3-4 injections (the last one made 24 hours before intoxication) has been found to enhance the resistance of the animals to the subcutaneous injection of type A C. perfringens toxin by 40-60% and to its intraperitoneal injection by 60-97%.
对575只非近交系白色小鼠进行的实验表明,作为一种商业免疫刺激剂的灵菌红素的给药可增强动物对A型产气荚膜梭菌毒素的非特异性抵抗力。已发现,分3至4次注射(最后一次在中毒前24小时进行)的灵菌红素可使动物对皮下注射A型产气荚膜梭菌毒素的抵抗力提高40%至60%,对腹腔注射该毒素的抵抗力提高60%至97%。