Liljencrantz Jaquette, Pitcher Mark H, Low Lucie A, Bauer Lucy, Bushnell M Catherine
Pain and Integrative Neuroscience Laboratory, National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, MD 20892, USA.
Science. 2017 Jul 14;357(6347). doi: 10.1126/science.aan4749.
Yu (Reports, 10 March 2017, p. 1072) state that contagious itch occurs in mice based on imitative scratching in normal mice observing excessive scratching in genetically modified demonstrator mice. However, despite employing multiple behavioral analysis approaches, we were unable to extend these findings to normal mice observing the well-established histamine model of acute itch in demonstrator mice.
于(《报告》,2017年3月10日,第1072页)指出,传染性瘙痒在小鼠中发生,是基于正常小鼠在观察转基因示范小鼠过度抓挠时的模仿抓挠行为。然而,尽管采用了多种行为分析方法,我们仍无法将这些发现扩展到正常小鼠观察示范小鼠中成熟的急性瘙痒组胺模型的情况。