Altschuler R A, Hoffman D W, Wenthold R J
Am J Otolaryngol. 1986 Mar-Apr;7(2):100-6. doi: 10.1016/s0196-0709(86)80038-2.
Many neurotransmitter candidates have been identified in the cochlea and cochlear nucleus with the use of immunocytochemical techniques. Choline acetyltransferase immunoreactivity suggests acetylcholine as a transmitter of medial and lateral efferent systems in the cochlea. Immunoreactivities to enkephalins, dynorphins, calcitonin gene-related peptide, and tyrosine hydroxylase (a marker for dopamine) are also found in lateral efferents. Choline acetyltransferase, enkephalin, and dynorphin immunoreactivities are co-contained in neurons of the lateral system. In the anteroventral cochlear nucleus, the inhibitory amino acid transmitters, gamma aminobutyric acid (GABA), and glycine, as well as the presumed excitatory amino acid transmitter of the auditory nerve, have been directly or indirectly localized, immunocytochemically, to discrete populations of terminals on spherical cells with distinct morphologic characteristics.
利用免疫细胞化学技术，在耳蜗和蜗神经核中已鉴定出许多可能的神经递质。胆碱乙酰转移酶免疫反应表明乙酰胆碱是耳蜗内侧和外侧传出系统的一种递质。在外侧传出纤维中也发现了对脑啡肽、强啡肽、降钙素基因相关肽和酪氨酸羟化酶（多巴胺的标志物）的免疫反应。胆碱乙酰转移酶、脑啡肽和强啡肽免疫反应共同存在于外侧系统的神经元中。在前庭蜗神经核中，抑制性氨基酸递质γ-氨基丁酸（GABA）和甘氨酸，以及推测的听神经兴奋性氨基酸递质，已通过免疫细胞化学方法直接或间接地定位到具有不同形态特征的球形细胞上离散的终末群体。
