Murphy David J, Gill Ritu R
Division of Thoracic Imaging, Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Ann Transl Med. 2017 Jun;5(11):241. doi: 10.21037/atm.2017.05.23.
Malignant pleural mesothelioma (MPM) is a highly malignant pleural neoplasm with a dismal prognosis. Multimodality approach including surgery and chemotherapy are utilized to treat patients with resectable disease. Clinical staging allows for selection of patients for treatment strategies, but has not been found to be prognostic and is plagued by high interobserver variability. Tumor volume measurement on cross-sectional imaging has emerged as a potential quantitative tool with prognostic significance. This review focuses on volumetric assessment from cross-sectional imaging (CT, MRI, F-FDG PET/CT) and the potential prognostic benefit and applications.
恶性胸膜间皮瘤(MPM)是一种预后极差的高度恶性胸膜肿瘤。包括手术和化疗在内的多模式方法用于治疗可切除疾病的患者。临床分期有助于选择治疗策略的患者,但尚未发现其具有预后价值,且存在较高的观察者间变异性。横断面成像上的肿瘤体积测量已成为一种具有预后意义的潜在定量工具。本综述重点关注横断面成像(CT、MRI、F-FDG PET/CT)的容积评估以及潜在的预后益处和应用。