关于与干细胞产品心肌内共同注射的MACS®微珠命运的数据。
Data on the fate of MACS® MicroBeads intramyocardially co-injected with stem cell products.
作者信息
Müller Paula, Gaebel Ralf, Lemcke Heiko, Steinhoff Gustav, David Robert
机构信息
Reference and Translation Center for Cardiac Stem Cell Therapy (RTC), Department of Cardiac Surgery, Rostock University Medical Center, Schillingallee 69, 18057 Rostock, Germany.
Department Life, Light and Matter of the Interdisciplinary Faculty at Rostock University, Albert-Einstein Straße 25, 18059 Rostock, Germany.
出版信息
Data Brief. 2017 Jun 24;13:569-574. doi: 10.1016/j.dib.2017.06.035. eCollection 2017 Aug.
The data presented in this article are related to the research article "Intramyocardial Fate and Effect of Iron Nanoparticles co-injected with MACS® purified Stem Cell Products" (Müller et al., 2017) [1]. This article complements the cellular localization of superparamagnetic iron dextran particles (MACS® MicroBeads) used for magnetic activated cell sorting (MACS®). Data evaluate the time-dependent detachment of these nanoparticles from CD133 haematopoietic stem cells (HSCs) and CD271 mesenchymal stem cells (MSCs). Furthermore, the influence of these stem cells as well as of nanoparticles on cardiac remodeling processes after myocardial infarction (MI) was investigated.
本文所呈现的数据与研究论文《与MACS®纯化干细胞产品共注射的铁纳米颗粒在心肌内的命运及作用》（Müller等人，2017年）[1]相关。本文补充了用于磁性激活细胞分选（MACS®）的超顺磁性葡聚糖铁颗粒（MACS®微珠）的细胞定位信息。数据评估了这些纳米颗粒从CD133造血干细胞（HSCs）和CD271间充质干细胞（MSCs）上随时间的脱离情况。此外，还研究了这些干细胞以及纳米颗粒对心肌梗死（MI）后心脏重塑过程的影响。
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