非酶级联扩增策略用于疾病生物标志物的比色分析。
A non-enzyme cascade amplification strategy for colorimetric assay of disease biomarkers.
机构信息
Department of Chemistry, Michigan Technological University, Houghton, Michigan 49931, USA.
出版信息
Chem Commun (Camb). 2017 Aug 10;53(65):9055-9058. doi: 10.1039/c7cc04521b.
PMID:28707690
Abstract
A non-enzyme cascade amplification strategy, based on the dissolution of Ag nanoparticles and a Pt nanocube-catalyzed reaction, for colorimetric assay of disease biomarkers was developed. This strategy overcomes the intrinsic limitations of enzymes involved in conventional enzymatic amplification techniques, thanks to the utilization of noble-metal nanostructures with superior properties.
摘要
一种基于银纳米粒子溶解和 Pt 纳米立方体催化反应的非酶级联扩增策略被开发用于疾病生物标志物的比色分析。由于利用了具有优异性能的贵金属纳米结构，该策略克服了传统酶促扩增技术中涉及的酶的固有局限性。
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