Michelotti Francesco, Rizzo Riccardo, Sinibaldi Alberto, Munzert Peter, Wächter Christoph, Danz Norbert
Opt Lett. 2017 Jul 15;42(14):2798-2801. doi: 10.1364/OL.42.002798.
We report on the fabrication and physical characterization of optical biosensors implementing simultaneous label-free and fluorescence detection and taking advantage of the excitation of Bloch surface waves at a photonic crystal's truncation interface. Two types of purposely designed one-dimensional photonic crystals on molded organic substrates with micro-optics were fabricated. These crystals feature either high or low finesse of the Bloch surface wave resonances and were tested on the same optical readout system. The experimental results show that designing biochips with a large resonance quality factor does not necessarily lead in the real case to an improvement of the biosensor performance. The conditions for optimal biochip design and operation of the complete bio-sensing platform are established.
我们报告了光学生物传感器的制造及其物理特性，该传感器实现了无标记和荧光同时检测，并利用了光子晶体截断界面处布洛赫表面波的激发。在带有微光学器件的模制有机基板上制造了两种专门设计的一维光子晶体。这些晶体具有高或低精细度的布洛赫表面波共振，并在同一光学读出系统上进行了测试。实验结果表明，在实际情况下，设计具有大共振品质因数的生物芯片并不一定会提高生物传感器的性能。建立了完整生物传感平台的最佳生物芯片设计和操作条件。
