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酶处理对小肠钙吸收的影响:大鼠与兔转运机制的比较研究

Effect of enzymatic treatment on calcium absorption by small intestine: a comparative study between rat and rabbit transport mechanisms.

作者信息

Saadeh G M, Murr M, Nassar C F

出版信息

Comp Biochem Physiol A Comp Physiol. 1986;83(3):539-41. doi: 10.1016/0300-9629(86)90142-8.

DOI:10.1016/0300-9629(86)90142-8
PMID:2870848
Abstract

Calcium absorption by the small intestine of rat and rabbit reached steady state after 60 min of incubation with intracellular to extracellular ratio of 2.0. Trypsin and neuraminidase significantly inhibited (P less than 0.05) calcium accumulation in rat small intestine. These enzymes showed no significant effect (P greater than 0.05) on calcium transport across rabbit small intestine. The inhibitory action of trypsin and neuraminidase on calcium accumulation by the rat small intestine does not involve the influx of calcium into the intestinal cells.

摘要

大鼠和家兔小肠对钙的吸收在细胞内与细胞外比例为2.0的情况下孵育60分钟后达到稳定状态。胰蛋白酶和神经氨酸酶显著抑制(P<0.05)大鼠小肠中的钙积累。这些酶对家兔小肠的钙转运没有显著影响(P>0.05)。胰蛋白酶和神经氨酸酶对大鼠小肠钙积累的抑制作用不涉及钙流入肠细胞。

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